The MIDIbox LC is a MIOS based application which emulates a Logic Control / Mackie Control.
This protocol is supported by a lot of host applications.
Last info (report about “Mackie Control Univsersal” from the german magazine Keyboards, issue 01-2005, page 110 ff.):
MotU Digital Performer
Steinberg Cubase SX/SL and Nuendo
Adobe Audition (formerly known as Cool Edit Pro)
APB Tools TH-S
Ableton Live! 5
Vegas Video Studio